Anti-Human CD20 mAb
![Anti-Human CD20 mAb Anti-Human CD20 mAb](https://www.tlbiotechnology.com/image/cache/catalog/CD20%20antibody-550x550h.png)
- Stock: In Stock
- Model: GMP-TL502
Available Options
CD20 is a specific signature molecule on the surface of B lymphocytes and is expressed on more than 95% of normal or malignant B lymphocytes. There is no expression of CD20 antigen in hematopoietic stem cells, progenitor cells, and other normal tissues. It consists of 297 amino acids with a molecular weight of 33 kD. CD20 has no internalization or cell surface shedding after binding with anti-CD20 mAb , which is an ideal antigen in the treatdment of B lymphocyte-related diseases. Anti-CD20 mAb can kill most of the lymphoma cells expressing CD20 molecules and normal B cells. Innate normal B cells are not affected by anti-CD20 mAb and can reconstruct B cell population. Therefore, anti-CD20 monoclonal antibodies are increasingly used in the treatment of B cell-related diseases
Cytokines | |
QC Testing Purity | > 90 % as determined by SDS-PAGE. |
Endotoxin | < 0.1EU per μg of the protein as determined by the LAL method. |
Formulation | Supplied as a 0.22μm filtered solution in PBS, PH 7.4 |
Monoclonal Antibodies | |
Biological activity | The binding rate with PBMCs |
Expression Host | CHO cells |
Purification: | Protein A purified from cell culture supernatant. |
Stability & Storage | 24 months at 2℃ to 8℃. Avoid repeated freeze-thaw cycles. |
Thumb | File information |
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GMP-TL502_SDS.pdf File Size92.61KB Downloaded: 54 |
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GMP-TL502_Product Sheet.pdf File Size79.65KB Downloaded: 59 |