Recombinant Human Vitronectin Protein

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Model: GMP-TL651

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Recombinant human vitronectin protein efficiently binds to extracellular matrices and is primarily used to promote cell adhesion by coating plates or flasks. In the matrix, vitronectin can support cell adhesion by binding to various integrins and other proteoglycans. In addition, vitronectin can function as a chemically defined matrix component in human embryonic stem cell regeneration media.

Cytokines
Expression Host	HEK293 Cells
Synonym	V75, Vitronectin, VN, VTN, S-protein, Serum-spreading factor
Protein Sequence	A DNA sequence encoding the human Vitronectin（NP_000629.3）was expressed with a polyhistidine tag at the C-terminus.
Molecular Mass	The Recombinant Human Vitronectin consists of 465 amino acids and predicts a molecular mass of 53kDa.
QC Testing Purity	> 90 % as determined by SDS-PAGE.
Endotoxin	< 0.1EU per μg of the protein as determined by the LAL method.
Activity	Promote expansion of iPSC, ED₅₀≤2.4μg/mL.
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 6% mannitol are added as protectants before lyophilization.
Stability	Samples are stable for up to 24 months from date of receipt at 4 ℃. Recommend to aliquot the protein into smaller quantities for optimal storage. Avoid repeated freeze-thaw cycles.